The science

An evidence framework, not a marketing list.

Every active we will formulate is graded against published human evidence and an internal safe-upper-limit table. The grade and the reasoning ship with your formulation record, so you and your physician always know why a milligram is in your bottle.

Recommended actives

Multiple randomized controlled trials or large meta-analyses support a dose-response effect at the doses we offer. Vitamin D3, magnesium, omega-3 EPA/DHA, creatine monohydrate.

Available, with context

Mechanistic plausibility and moderate human evidence. We will formulate but the pharmacist note will spell out the limits of the data. NAC, L-theanine, berberine, alpha-lipoic acid.

Practitioner-only

Early evidence, narrow indication, or required practitioner supervision. Only formulated when a licensed provider submits the protocol. NMN, methylene blue at trace doses.

We will not formulate

Insufficient safety data, contaminated supply chain, or unresolved drug interactions. We publish the X-list and update it quarterly.

Our safe-upper-limit table

Before a milligram value is accepted, the formula is auto-screened against Tolerable Upper Intake Levels (UL) from the National Academies and our internal conservative practitioner ceiling. If the requested dose exceeds either, a pharmacist reviews it manually before production.

Browse the active catalog →

Active	RDA	UL	Vitamet ceiling
Vitamin D3	15 mcg	100 mcg	125 mcg*
Zinc	11 mg	40 mg	30 mg
Magnesium (supplemental)		350 mg	400 mg
Vitamin B6 (P5P)	1.3 mg	100 mg	50 mg
NAC			1200 mg
Selenium	55 mcg	400 mcg	200 mcg

* Vitamin D3 above the UL is only formulated with a physician's signed protocol.

References we use

We anchor our grading and dosing decisions to public, primary sources.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.